BI487蛋白质与酶工程课程教学大纲

蛋白质与酶工程课程教学大纲课程基本信息(Course Information)课程代码*学时*学分B1487322(Course Code)(Credit Hours）(Credits)*课程名称(中文)蛋白质与酶工程Course Title(Functions and Applications of Proteins Enzymes*课程性质培养计划内课程(Course Type)授课对象生物工程、生物技术专业本科生(Target Audience*授课语言中文(Language of Instruction)*开课院系生命科学技术学院(School)先修课程《生物化学》、《有机化学》、《微生物学》、《分子遗传学》(Prerequisite）Biochemistry,Organic chemistry,Microbiology,Molecular genetics授课教师由德林课程网址ftp://public.sjtu.edu.cn/(Instructor(Course Webpage)本课程将提供一个对蛋白质功能、发挥功能的机制以及其应用的详细了解，“些主题将包括蛋白质功能的结构基础、蛋白质和酶的作用机制、蛋白质折叠和组装、蛋白质翻译后定位与修饰、蛋白质化学、蛋白质重组表达与分离、蛋白质表征、蛋白质功能确认方法、蛋白质相互作用及其辅因子、蛋白质与酶的分子改*课程简介(Description)造与应用。课程的主要目的是使授课学生理解并掌握蛋白质科学的基本理论，熟悉蛋白质和酶用于生产有用物质所需要的综合性的，跨学科的方法。了解蛋白质科学相关新进展和典型实例，拓展对生物科学相关领域的思维能力和综合视野。This course will provide a detailed understanding of the functional properties,functional mechanism and applications of proteins and enzymes,and will includetopics such as structural foundation of functional proteins,mechanism of proteinaction,protein localization and posttranslational modification,protein chemistry,protein isolation and recombination expression,characterisation techniques,protein-ligand and protein-protein interactions,strategy for engineering proteins,and*课程简介(Description)applications of proteins and enzymes.the purpose of the course is to give biologicalengineering undergraduates an understanding and an overview of the subject ofprotein science.The fundamentals of enzyme-catalyzed reactions will be introduced,especially as they apply to large scale production of small molecules.Th is course aimsto familiarize participants with the integrated,interdisciplinary approach required toutilize the functional proteins and enzymes for applications.