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中华危重病急救医学2024年7月第36卷第7期Chin Crit Care Med,July2024,Vol.36,No.7673·专家共识·中国重症患者肠外营养治疗临床实践专家共识(2024)浙江省医学会重症医学分会通信作者:江荣林,Email:jiangronglin(@l26.com【摘要】重症患者营养不良发生率高,容易导致感染、CU获得性肌无力等不良预后,如何改善重症患者营养状况是目前一个重要难题。肠外营养(PN)是医学营养的重要组成部分,但目前如何针对重症患者实施合理规范的PN尚有较多争议。为进一步规范重症患者的P策略,浙江省医学会重症医学分会召集重症医学领域专家,制定了《中国重症患者肠外营养治疗临床实践专家共识(2024)》。该共识基于GRADE证据质量分级标准,以问题为导向,从PN时机、适宜人群、营养方案及成分比例等多方面总结循证医学证据,为临床营养实践中PN的规范化和标准化实施提供专业建议。【关键词】肠外营养;重症;专家共识义)实践指南注册:国际实践指南注册与透明化平台,PREPARE-2024CN753D0I:10.3760/cmaj.cn121430-20240123-00080Expert consensus on clinical practice of parenteral nutrition therapy for critically ill patients in China (2024)Zhejiang Medical Association Critical Care Medicine BranchCorresponding author:Jiang Ronglin,Email jiangronglin@126.com[Abstract)Critical patients have a high incidence of malnutrition.which can lead to adverse outcomes such asinfections and ICU-acquired weakness.Improving the nutritional status of critically ill patients is currently an importantchallenge.Parenteral nutrition(PN)is an important component of medical nutrition,but there is still much controversyover how to implement a reasonable and standardized PN for critically ill patients.To further standardize the PN strategyfor critically ill patients,the Critical Care Medicine Branch of the Zhejiang Medical Association convened experts inthe field of critical care medicine and formulated the Expert consensus on clinical practice of parenteral nutrition therapyfor critically ill patients in China (2024).This consensus is based on the GRADE evidence quality grading standard,problem oriented,and summarizes evidence-based medieine eyidence from multiple aspects such as PN timing.suitable population,nutritional plan,and ingredient ratio,providing professional suggestions for the standardization andaeciaeRenmiedhaglennSSimplementation of PN in clinical nutrition practice.Practice Guideline Registration:Practice Guideline Registration for Transparency.PREPA RE-2024CN753D0L:10.3760/cmaj.cm121430-20240123-00080重症患者营养不良发生率高达30%~50%,可号证据质量分级标准,以临床问题为导向,根据目前循导致总住院时间及重症监护病房(intensive care unit,证医学证据,制定了《中国重症患者肠外营养治疗ICU)住院时间明显延长,感染、ICU获得性肌无力?临床实践专家共识(2024)》,并请40位专家为每条等并发症显著增加【2]。医学营养治疗是重症患者推荐意见进行评分,以均数±标准差(x士s)列于推的重要治疗手段之一,在患者血流动力学及内环境荐意见之后作为推荐强度,为临床营养实践中PN的基本稳定的情况下,应实施积极的医学营养治疗,其规范化和标准化实施提供专业建议。本共识已通过中,肠外营养(parenteral nutrition,PN)是医学营养治国际实践指南注册与透明化平台(Practice Guideline疗的重要组成部分。国内外指南也推荐在肠内营养Registration for Transparency,PREPARE)进行了注册(enteral nutrition,EN)禁忌或不足时,可进行全胃肠(注册号:PREPARE-2024CN753)。外营养(total parenteral nutrition,TPN)或补充性肠外1对于有高营养风险或严重营养不良的重症患者,营养(supplementary parenteral nutrition,SPN)治疗。什么时候是PN启动的时机?目前认为,合理规范的PN可改善重症患者的临床既往研究表明,与PN相比,早期EN可降低重预后,但有关P的启动时机、方法、成分及剂量等症患者感染发生率,缩短ICU住院时间[s],因此建议问题仍然存在很多争议[。因此,浙江省医学会对于存在高营养风险或严重营养不良的重症患者,重症医学分会召集重症医学领域专家,基于GRADE应在不能耐受EN时才启动PN,且在未尝试所有优
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