BI470系统生物学课程教学大纲

系统生物学课程教学大纲课程基本信息(Course Information)课程代码学时学分Bl470(Credit322(Course Code)(Credits)Hours)课程名称系统生物学(Course Name)Systems Biology课程性质培养计划内课程(Course Type)授课对象(Target生物信息学专业本科生Audience)授课语言(Language of中外双语Instruction)开课院系生命科学学院(School)先修课程生物信息学(Prerequisite)授课教师课程网址王卓(Coursehttp://cbb.sjtu.edu.cn/~zwang/sysbio/(TeacherWebpage)主要介绍系统生物学的发展过程、基本概念和研究内容，包括基因组学、转录组学、蛋白质组学、代谢组学等不同层次的概念和研究领域，生物网络拓扑结构分析与动态建模，代谢流模拟及在代谢工程与健康领域的应用等。培养学生对*课程简介前沿交叉科学的兴趣，了解系统生物学领域的进展和存在问题、掌握基本研究方(Description)法，具备用计算手段解决生物学问题的能力。并通过分组大作业，让2-3名同学合作完成一个利用生物网络解决问题的实例，提高学生的科研能力和团队合作精神。The history,theory,and main topics of systems biology will be introduced in thiscourse,including genomics,transcriptomics,proteomics,metabolomics,biologicalnetwork topology and modeling,and metabolic flux simulation.We will talk abouthow to apply these strategies to guide metabolic engineering and identify drug targets*课程简介and biomarkers for human health.By learning this course,the students will be(Description)】interested in the interdisciplinary filed,learn the development and challenge ofsystems biology,and be able to use computational methods to solve biologicalquestions.In addition,2-3 students will be asked to form a team and perform a casestudy on biological network modeling,so that their research skills and teamworkabilities can be improved.